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Quantitative relationship between functionally active telomerase and major telomerase components (hTERT and hTR) in acute leukaemia cells

Functionally active telomerase is affected at various steps including transcriptional and post-transcriptional levels of major telomerase components (hTR and human telomerase reverse transcriptase (hTERT)). We therefore developed a rapid and sensitive method to quantify hTERT and its splicing varian...

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Detalles Bibliográficos
Autores principales: Ohyashiki, J H, Hisatomi, H, Nagao, K, Honda, S, Takaku, T, Zhang, Y, Sashida, G, Ohyashiki, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361762/
https://www.ncbi.nlm.nih.gov/pubmed/15827550
http://dx.doi.org/10.1038/sj.bjc.6602546