Plucked human hair as a tissue in which to assess pharmacodynamic end points during drug development studies

We have demonstrated the feasibility of detecting and quantifying six cell-cycle-related nuclear markers (Ki67, pRb, p27, phospho-p27 (phosphorylated p27), phospho-pRb (phosphorylated pRb), phospho-HH3 (phosphorylated histone H3)) in plucked human scalp and eyebrow hair. Estimates of the proportion...

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Detalles Bibliográficos
Autores principales: Camidge, D R, Randall, K R, Foster, J R, Sadler, C J, Wright, J A, Soames, A R, Laud, P J, Smith, P D, Hughes, A M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361775/
https://www.ncbi.nlm.nih.gov/pubmed/15886708
http://dx.doi.org/10.1038/sj.bjc.6602558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361775/
https://www.ncbi.nlm.nih.gov/pubmed/15886708
http://dx.doi.org/10.1038/sj.bjc.6602558

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