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Role of insulin-like growth factor 1 receptor signalling in cancer
The insulin-like growth factor (IGF-1) signalling is highly implicated in cancer. In this signalling the IGF-1 receptor (IGF-1R) is unquestionable, the predominating single factor. IGF-1R is crucial for tumour transformation and survival of malignant cell, but is only partially involved in normal ce...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361813/ https://www.ncbi.nlm.nih.gov/pubmed/15956962 http://dx.doi.org/10.1038/sj.bjc.6602627 |