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Role of insulin-like growth factor 1 receptor signalling in cancer

The insulin-like growth factor (IGF-1) signalling is highly implicated in cancer. In this signalling the IGF-1 receptor (IGF-1R) is unquestionable, the predominating single factor. IGF-1R is crucial for tumour transformation and survival of malignant cell, but is only partially involved in normal ce...

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Detalles Bibliográficos
Autores principales: Larsson, O, Girnita, A, Girnita, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361813/
https://www.ncbi.nlm.nih.gov/pubmed/15956962
http://dx.doi.org/10.1038/sj.bjc.6602627