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Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects

Dendritic and lymphoid ‘exosomes’ regulate immune activation. Tumours release membranous material mimicking these ‘exosomes,’ resulting in deletion of reactive lymphocytes. Tumour-derived ‘exosomes’ have recently been explored as vaccines, without analysis of their immunologic consequences. This inv...

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Detalles Bibliográficos
Autores principales: Taylor, D D, Gerçel-Taylor, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361848/
https://www.ncbi.nlm.nih.gov/pubmed/15655551
http://dx.doi.org/10.1038/sj.bjc.6602316