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Tumour-derived exosomes and their role in cancer-associated T-cell signalling defects
Dendritic and lymphoid ‘exosomes’ regulate immune activation. Tumours release membranous material mimicking these ‘exosomes,’ resulting in deletion of reactive lymphocytes. Tumour-derived ‘exosomes’ have recently been explored as vaccines, without analysis of their immunologic consequences. This inv...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361848/ https://www.ncbi.nlm.nih.gov/pubmed/15655551 http://dx.doi.org/10.1038/sj.bjc.6602316 |