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Role of survivin and its splice variants in tumorigenesis
Survivin, a unique member of the inhibitor of apoptosis (IAP) protein family, is highly expressed in cancer but is undetectable in nonproliferating normal adult tissues, suggesting a potential role in tumorigenesis. Differential splicing of survivin pre-mRNA results in three new survivin variants, s...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361850/ https://www.ncbi.nlm.nih.gov/pubmed/15611788 http://dx.doi.org/10.1038/sj.bjc.6602340 |