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A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells

There is increasing evidence that vascular endothelial growth factor (VEGF) has autocrine as well as paracrine functions in tumour biology. Vascular endothelial growth factor-mediated cell survival signalling occurs via the classical tyrosine kinase receptors Flt-1, KDR/Flk-1 and the more novel neur...

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Detalles Bibliográficos
Autores principales: Barr, M P, Byrne, A M, Duffy, A M, Condron, C M, Devocelle, M, Harriott, P, Bouchier-Hayes, D J, Harmey, J H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361857/
https://www.ncbi.nlm.nih.gov/pubmed/15655556
http://dx.doi.org/10.1038/sj.bjc.6602308