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Lack of EGF receptor contributes to drug sensitivity of human germline cells

Germline mutations have been associated with generation of various types of tumour. In this study, we investigated genetic alteration of germline tumours that affect the drug sensitivity of cells. Although all germline tumour cells we tested were hypersensitive to DNA-damaging drugs, no significant...

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Detalles Bibliográficos
Autores principales: Park, S-J, Armstrong, S, Kim, C-H, Yu, M, Robertson, K, Kelley, M R, Lee, S-H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361860/
https://www.ncbi.nlm.nih.gov/pubmed/15655552
http://dx.doi.org/10.1038/sj.bjc.6602315