Early endostatin treatment inhibits metastatic seeding of murine colorectal cancer cells in the liver and their adhesion to endothelial cells

Endostatin, a carboxy-terminal fragment of collagen XVIII, potently inhibits angiogenesis and tumour growth, presumably through induction of apoptosis in endothelial cells and/or inhibition of their migration. Here we have tested how the timing of recombinant human endostatin (rh-E) administration a...

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Detalles Bibliográficos
Autores principales: te Velde, E A, Reijerkerk, A, Brandsma, D, Vogten, J M, Wu, Y, Kranenburg, O, Voest, E E, Gebbink, M, Borel Rinkes, I H M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361873/
https://www.ncbi.nlm.nih.gov/pubmed/15700042
http://dx.doi.org/10.1038/sj.bjc.6602385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361873/
https://www.ncbi.nlm.nih.gov/pubmed/15700042
http://dx.doi.org/10.1038/sj.bjc.6602385

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