Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer

DNA hypomethylation may increase the risk of colorectal cancer. The main aim of this study was to assess the influence of folate status (serum and erythrocyte folate and plasma homocysteine concentrations) on DNA methylation. Methylenetetrahydrofolate reductase (MTHFR 677C → T and 1298A → C), methio...

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Detalles Bibliográficos
Autores principales: Pufulete, M, Al-Ghnaniem, R, Rennie, J A, Appleby, P, Harris, N, Gout, S, Emery, P W, Sanders, T A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361912/
https://www.ncbi.nlm.nih.gov/pubmed/15726099
http://dx.doi.org/10.1038/sj.bjc.6602439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361912/
https://www.ncbi.nlm.nih.gov/pubmed/15726099
http://dx.doi.org/10.1038/sj.bjc.6602439

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