MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling

It has been shown that in hereditary and most sporadic colon tumours, components of the Wnt pathway are mutated. The Wnt target MET has been implicated in the development of colon cancer. Here, we show that overexpression of wild-type or a constitutively activated form of MET in colon epithelial cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Boon, E M J, Kovarikova, M, Derksen, P W B, van der Neut, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361927/
https://www.ncbi.nlm.nih.gov/pubmed/15785735
http://dx.doi.org/10.1038/sj.bjc.6602405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361927/
https://www.ncbi.nlm.nih.gov/pubmed/15785735
http://dx.doi.org/10.1038/sj.bjc.6602405

Ejemplares similares