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Targeting of Rad51-dependent homologous recombination: implications for the radiation sensitivity of human lung cancer cell lines

The aim of the present work was to study the role of Rad51-dependent homologous recombination in the radiation response of non-small-cell lung cancer (NSCLC) cell lines. A dose- and time-dependent increase in the formation of Rad51 and γ-H2AX foci with a maximum at about 4 and 1 h after irradiation,...

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Detalles Bibliográficos
Autores principales: Sak, A, Stueben, G, Groneberg, M, Böcker, W, Stuschke, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361929/
https://www.ncbi.nlm.nih.gov/pubmed/15785736
http://dx.doi.org/10.1038/sj.bjc.6602457