Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations

The purpose of this study was to determine activity of temozolomide combined with paclitaxel or epothilone B in vitro, and to investigate the combination of temozolomide with paclitaxel in a Phase I clinical trial. Melanoma cell lines A375P and DX3 were treated with temozolomide and either paclitaxe...

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Detalles Bibliográficos
Autores principales: Azzabi, A, Hughes, A N, Calvert, P M, Plummer, E R, Todd, R, Griffin, M J, Lind, M J, Maraveyas, A, Kelly, C, Fishwick, K, Calvert, A H, Boddy, A V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361941/
https://www.ncbi.nlm.nih.gov/pubmed/15756276
http://dx.doi.org/10.1038/sj.bjc.6602438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361941/
https://www.ncbi.nlm.nih.gov/pubmed/15756276
http://dx.doi.org/10.1038/sj.bjc.6602438

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