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Mutation screening and association study of RNASEL as a prostate cancer susceptibility gene

To date, germline mutations have been found in three candidate genes for hereditary prostate cancer: ELAC2 at 17p11, RNASEL at 1q25 and MSR1 at 8p22. RNASEL, encoding the 2′,5′-oligoadenylate-dependant RNase L, seems to have rare mutations in different ethnicities, such as M1I in Afro-Americans, E26...

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Detalles Bibliográficos
Autores principales: Maier, C, Haeusler, J, Herkommer, K, Vesovic, Z, Hoegel, J, Vogel, W, Paiss, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361943/
https://www.ncbi.nlm.nih.gov/pubmed/15714208
http://dx.doi.org/10.1038/sj.bjc.6602401