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K-ras mutation in the endometrium of tamoxifen-treated breast cancer patients, with a comparison of tamoxifen and toremifene

The putative presence of a mutation in codon 12 of the K-ras gene was investigated in the endometrium of tamoxifen (TAM) and toremifene (TOR)-treated breast cancer patients. DNA was extracted from fresh cytologic samples of the endometrium in 86 TAM and 21 TOR-treated breast cancer patients. Mutatio...

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Detalles Bibliográficos
Autores principales: Hachisuga, T, Tsujioka, H, Horiuchi, S, Udou, T, Emoto, M, Kawarabayashi, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361944/
https://www.ncbi.nlm.nih.gov/pubmed/15756272
http://dx.doi.org/10.1038/sj.bjc.6602456