Aspirin-induced nuclear translocation of NFκB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency

Substantial evidence indicates nonsteroidal anti-inflammatory drugs (NSAIDs) protect against colorectal cancer (CRC). However, the molecular basis for this anti-tumour activity has not been fully elucidated. We previously reported that aspirin induces signal-specific IκBα degradation followed by NFκ...

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Detalles Bibliográficos
Autores principales: Din, F V N, Stark, L A, Dunlop, M G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361954/
https://www.ncbi.nlm.nih.gov/pubmed/15770215
http://dx.doi.org/10.1038/sj.bjc.6602455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361954/
https://www.ncbi.nlm.nih.gov/pubmed/15770215
http://dx.doi.org/10.1038/sj.bjc.6602455

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