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Aspirin-induced nuclear translocation of NFκB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency
Substantial evidence indicates nonsteroidal anti-inflammatory drugs (NSAIDs) protect against colorectal cancer (CRC). However, the molecular basis for this anti-tumour activity has not been fully elucidated. We previously reported that aspirin induces signal-specific IκBα degradation followed by NFκ...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361954/ https://www.ncbi.nlm.nih.gov/pubmed/15770215 http://dx.doi.org/10.1038/sj.bjc.6602455 |