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A modified Trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer
The immunohistochemical determination of HER-2 to identify patients with advanced breast cancer candidates for Trastuzumab treatment proved neither accurate nor fully reliable, possibly because none of the current reagents detects the specific antigenic site target of Trastuzumab. To circumvent this...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361978/ https://www.ncbi.nlm.nih.gov/pubmed/15812476 http://dx.doi.org/10.1038/sj.bjc.6602507 |