NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Paclitaxel (PTX) is one of the most effective anticancer agents. In clinical practice, however, high incidences of adverse reactions of the drug, for example, neurotoxicity, myelosuppression, and allergic reactions, have been reported. NK105, a micellar nanoparticle formulation, was developed to ove...

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Detalles Bibliográficos
Autores principales: Hamaguchi, T, Matsumura, Y, Suzuki, M, Shimizu, K, Goda, R, Nakamura, I, Nakatomi, I, Yokoyama, M, Kataoka, K, Kakizoe, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361981/
https://www.ncbi.nlm.nih.gov/pubmed/15785749
http://dx.doi.org/10.1038/sj.bjc.6602479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361981/
https://www.ncbi.nlm.nih.gov/pubmed/15785749
http://dx.doi.org/10.1038/sj.bjc.6602479

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