Indomethacin-induced activation of the death receptor-mediated apoptosis pathway circumvents acquired doxorubicin resistance in SCLC cells

Small-cell lung cancers (SCLCs) initially respond to chemotherapy but are often resistant at recurrence. A potentially new method to overcome resistance is to combine classical chemotherapeutic drugs with apoptosis induction via tumour necrosis factor (TNF) death receptor family members such as Fas....

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Detalles Bibliográficos
Autores principales: de Groot, D J A, Timmer, T, Spierings, D C J, Le, T K P, de Jong, S, de Vries, E G E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361992/
https://www.ncbi.nlm.nih.gov/pubmed/15812552
http://dx.doi.org/10.1038/sj.bjc.6602516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361992/
https://www.ncbi.nlm.nih.gov/pubmed/15812552
http://dx.doi.org/10.1038/sj.bjc.6602516

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