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Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases

Colorectal carcinomas (CRCs) with high microsatellite instability (MSI-H) share clinicopathological features distinctly different from their microsatellite stable (MSS) counterparts. Unlike MSS cancers, MSI-H CRCs occur predominantly in the right-sided colon and are often characterised by a strong l...

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Detalles Bibliográficos
Autores principales: Buckowitz, A, Knaebel, H-P, Benner, A, Bläker, H, Gebert, J, Kienle, P, von Knebel Doeberitz, M, Kloor, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362037/
https://www.ncbi.nlm.nih.gov/pubmed/15856045
http://dx.doi.org/10.1038/sj.bjc.6602534