A potent nonporphyrin class of photodynamic therapeutic agent: cellular localisation, cytotoxic potential and influence of hypoxia

We have developed a totally new class of nonporphyrin photodynamic therapeutic agents with a specific focus on two lead candidates azadipyrromethene (ADPM)01 and ADPM06. Confocal laser scanning microscopy imaging showed that these compounds are exclusively localised to the cytosolic compartment, wit...

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Detalles Bibliográficos
Autores principales: Gallagher, W M, Allen, L T, O'Shea, C, Kenna, T, Hall, M, Gorman, A, Killoran, J, O'Shea, D F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362044/
https://www.ncbi.nlm.nih.gov/pubmed/15841085
http://dx.doi.org/10.1038/sj.bjc.6602527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362044/
https://www.ncbi.nlm.nih.gov/pubmed/15841085
http://dx.doi.org/10.1038/sj.bjc.6602527

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