Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein Bim(EL) and induces apoptosis

Components of garlic (Allium sativum) can cause disruption of microtubules, cell cycle arrest, and apoptosis in cancer cells. We show here that a water-soluble extract of garlic arrested MDA-MB-435 cancer cells in mitosis and caused apoptosis. The proapoptotic BH3-only, bcl-2 family protein Bim(EL),...

Descripción completa

Detalles Bibliográficos
Autores principales: Lund, T, Stokke, T, Olsen, Ø E, Fodstad, Ø
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362050/
https://www.ncbi.nlm.nih.gov/pubmed/15827557
http://dx.doi.org/10.1038/sj.bjc.6602537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362050/
https://www.ncbi.nlm.nih.gov/pubmed/15827557
http://dx.doi.org/10.1038/sj.bjc.6602537

Ejemplares similares