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Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein Bim(EL) and induces apoptosis

Components of garlic (Allium sativum) can cause disruption of microtubules, cell cycle arrest, and apoptosis in cancer cells. We show here that a water-soluble extract of garlic arrested MDA-MB-435 cancer cells in mitosis and caused apoptosis. The proapoptotic BH3-only, bcl-2 family protein Bim(EL),...

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Detalles Bibliográficos
Autores principales:	Lund, T, Stokke, T, Olsen, Ø E, Fodstad, Ø
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362050/ https://www.ncbi.nlm.nih.gov/pubmed/15827557 http://dx.doi.org/10.1038/sj.bjc.6602537

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