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Defects in muscarinic receptor-coupled signal transduction in isolated parotid gland cells after in vivo irradiation: evidence for a non-DNA target of radiation

Radiation-induced dysfunction of normal tissue, an unwanted side effect of radiotherapeutic treatment of cancer, is usually considered to be caused by impaired loss of cell renewal due to sterilisation of stem cells. This implies that the onset of normal tissue damage is usually determined by tissue...

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Detalles Bibliográficos
Autores principales: Coppes, R P, Meter, A, Latumalea, S P, Roffel, A F, Kampinga, H H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362077/
https://www.ncbi.nlm.nih.gov/pubmed/15668705
http://dx.doi.org/10.1038/sj.bjc.6602365