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Reducing the false positive rate in the non-parametric analysis of molecular coevolution

BACKGROUND: The strength of selective constraints operating on amino acid sites of proteins has a multifactorial nature. In fact, amino acid sites within proteins coevolve due to their functional and/or structural relationships. Different methods have been developed that attempt to account for the e...

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Detalles Bibliográficos
Autores principales: Codoñer, Francisco M, O'Dea, Shirley, Fares, Mario A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362121/
https://www.ncbi.nlm.nih.gov/pubmed/18402697
http://dx.doi.org/10.1186/1471-2148-8-106