The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

The Wild-type p53-induced phosphatase 1, Wip1 (or PPM1D), is unusual in that it is a serine/threonine phosphatase with oncogenic activity. A member of the type 2C phosphatases (PP2Cδ), Wip1 has been shown to be amplified and overexpressed in multiple human cancer types, including breast and ovarian...

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Detalles Bibliográficos
Autores principales: Lu, Xiongbin, Nguyen, Thuy-Ai, Moon, Sung-Hwan, Darlington, Yolanda, Sommer, Matthias, Donehower, Lawrence A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362138/
https://www.ncbi.nlm.nih.gov/pubmed/18265945
http://dx.doi.org/10.1007/s10555-008-9127-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362138/
https://www.ncbi.nlm.nih.gov/pubmed/18265945
http://dx.doi.org/10.1007/s10555-008-9127-x

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