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Deletions of the region 17p11-13 in advanced melanoma revealed by cytogenetic analysis and fluorescence in situ hybridization

The significance of the p53 tumour-suppressor gene in the oncogenesis of a variety of malignant tumours has been demonstrated over recent years. However, the role of p53 in human malignant melanoma is still unclear. Therefore, we investigated melanoma metastases from 11 patients cytogenetically and...

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Detalles Bibliográficos
Autores principales: Okamoto, I, Pirc-Danoewinata, H, Ackermann, J, Drach, J, Wadl, H Schlagbauer, Jansen, B, Wolff, K, Pehamberger, H, Marosi, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362169/
https://www.ncbi.nlm.nih.gov/pubmed/10408704
http://dx.doi.org/10.1038/sj.bjc.6690022