Bcl-2 overexpression blocks caspase activation and downstream apoptotic events instigated by photodynamic therapy

Treatment with the photosensitizer benzoporphyrin derivative monoacid ring A (BPD-MA, verteporfin) followed by irradiation with visible light induces apoptosis in human acute myelogenous leukaemia HL-60 cells. Photoactivation of BPD-MA induces procaspase 3 (CPP32/Yama/apopain) and procaspase 6 (Mch2...

Descripción completa

Detalles Bibliográficos
Autores principales: Granville, D J, Jiang, H, An, M T, Levy, J G, McManus, B M, Hunt, D W C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362171/
https://www.ncbi.nlm.nih.gov/pubmed/10408699
http://dx.doi.org/10.1038/sj.bjc.6690017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362171/
https://www.ncbi.nlm.nih.gov/pubmed/10408699
http://dx.doi.org/10.1038/sj.bjc.6690017

Ejemplares similares