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Bcl-2 overexpression blocks caspase activation and downstream apoptotic events instigated by photodynamic therapy

Treatment with the photosensitizer benzoporphyrin derivative monoacid ring A (BPD-MA, verteporfin) followed by irradiation with visible light induces apoptosis in human acute myelogenous leukaemia HL-60 cells. Photoactivation of BPD-MA induces procaspase 3 (CPP32/Yama/apopain) and procaspase 6 (Mch2...

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Detalles Bibliográficos
Autores principales:	Granville, D J, Jiang, H, An, M T, Levy, J G, McManus, B M, Hunt, D W C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362171/ https://www.ncbi.nlm.nih.gov/pubmed/10408699 http://dx.doi.org/10.1038/sj.bjc.6690017

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