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Telomerase activity in melanoma and non-melanoma skin cancer

Telomeres are specialized structures consisting of repeat arrays of TTAGGG(n) located at the ends of chromosomes. They are essential for chromosome stability and, in the majority of normal somatic cells, telomeres shorten with each cell division. Most immortalized cell lines and tumours reactivate t...

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Detalles Bibliográficos
Autores principales: Parris, C N, Jezzard, S, Silver, A, MacKie, R, McGregor, J M, Newbold, R F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362177/
https://www.ncbi.nlm.nih.gov/pubmed/10408692
http://dx.doi.org/10.1038/sj.bjc.6690010