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Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter

In the present study, we investigated the mechanisms controlling constitutive transcription of collagenase-1 and its repression by all-trans-retinoic acid (RA) in the highly invasive metastatic and oestrogen-receptor-negative breast cancer cell line MDA231. A combination of in vivo and in vitro expe...

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Detalles Bibliográficos
Autores principales: Benbow, U, Rutter, J L, Lowrey, C H, Brinckerhoff, C E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362185/
https://www.ncbi.nlm.nih.gov/pubmed/9888461
http://dx.doi.org/10.1038/sj.bjc.6690037