DNA methylation in the promoter region of the p16 (CDKN2/MTS-1/INK4A) gene in human breast tumours

The p16 (CDKN2/MTS-1/INK4A) gene is one of several tumour-suppressor genes that have been shown to be inactivated by DNA methylation in various human cancers including breast tumours. We have used bisulphite genomic sequencing to examine the detailed sequence specificity of DNA methylation in the Cp...

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Detalles Bibliográficos
Autores principales: Woodcock, D M, Linsenmeyer, M E, Doherty, J P, Warren, W D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362189/
https://www.ncbi.nlm.nih.gov/pubmed/9888465
http://dx.doi.org/10.1038/sj.bjc.6690041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362189/
https://www.ncbi.nlm.nih.gov/pubmed/9888465
http://dx.doi.org/10.1038/sj.bjc.6690041

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