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DNA methylation in the promoter region of the p16 (CDKN2/MTS-1/INK4A) gene in human breast tumours
The p16 (CDKN2/MTS-1/INK4A) gene is one of several tumour-suppressor genes that have been shown to be inactivated by DNA methylation in various human cancers including breast tumours. We have used bisulphite genomic sequencing to examine the detailed sequence specificity of DNA methylation in the Cp...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362189/ https://www.ncbi.nlm.nih.gov/pubmed/9888465 http://dx.doi.org/10.1038/sj.bjc.6690041 |