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Cell cycle perturbations and apoptosis induced by isohomohalichondrin B (IHB), a natural marine compound

Isohomohalichondrin B (IHB), a novel marine compound with anti-tumoral activity, extracted from the Lissodendorix sponge, inhibits GTP binding to tubulin, preventing microtubule assembly. Cell cycle perturbations and apoptosis induced by IHB were investigated on selected human cancer cell lines by u...

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Detalles Bibliográficos
Autores principales: Bergamaschi, D, Ronzoni, S, Taverna, S, Faretta, M, Feudis, P De, Faircloth, G, Jimeno, J, Erba, E, D'Incalci, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362206/
https://www.ncbi.nlm.nih.gov/pubmed/9888468
http://dx.doi.org/10.1038/sj.bjc.6690044