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Cell cycle perturbations and apoptosis induced by isohomohalichondrin B (IHB), a natural marine compound
Isohomohalichondrin B (IHB), a novel marine compound with anti-tumoral activity, extracted from the Lissodendorix sponge, inhibits GTP binding to tubulin, preventing microtubule assembly. Cell cycle perturbations and apoptosis induced by IHB were investigated on selected human cancer cell lines by u...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362206/ https://www.ncbi.nlm.nih.gov/pubmed/9888468 http://dx.doi.org/10.1038/sj.bjc.6690044 |