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Creatine and cyclocreatine treatment of human colon adenocarcinoma xenografts: (31)P and (1)H magnetic resonance spectroscopic studies
Creatine (Cr) and cyclocreatine (cyCr) have been shown to inhibit the growth of a variety of human and murine tumours. The purpose of this study was to evaluate the anti-tumour effect of these molecules in relation to drug accumulation, energy metabolism, tumour water accumulation and toxicity. Nude...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362210/ https://www.ncbi.nlm.nih.gov/pubmed/9888469 http://dx.doi.org/10.1038/sj.bjc.6690045 |