Ku70/80 gene expression and DNA-dependent protein kinase (DNA-PK) activity do not correlate with double-strand break (dsb) repair capacity and cellular radiosensitivity in normal human fibroblasts

The expression of the Ku70 and Ku80 genes as well as the activity of the DNA-dependent protein kinase (DNA-PK) were studied in 11 normal human fibroblast lines. The proteins studied are known to be part of a double-strand break (dsb) repair complex involved in non-homologous recombination, as was de...

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Detalles Bibliográficos
Autores principales: Kasten, U, Plottner, N, Johansen, J, Overgaard, J, Dikomey, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362213/
https://www.ncbi.nlm.nih.gov/pubmed/10098733
http://dx.doi.org/10.1038/sj.bjc.6690166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362213/
https://www.ncbi.nlm.nih.gov/pubmed/10098733
http://dx.doi.org/10.1038/sj.bjc.6690166

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