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Tissue inhibitor of metalloproteinases-1 (TIMP-1) mRNA is elevated in advanced stages of thyroid carcinoma

Tumour cell invasion and metastasis is a multistep process that involves the degradation of extracellular matrix proteins by matrix metalloproteinases (MMPs). Tissue inhibitors of metalloproteinases (TIMPs) act as negative regulators of MMPs and thus prevent tumour cell invasion and metastasis by pr...

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Detalles Bibliográficos
Autores principales: Shi, Y, Parhar, R S, Zou, M, Hammami, M M, Akhtar, M, Lum, Z-P, Farid, N R, Al-Sedairy, S T, Paterson, M C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362222/
https://www.ncbi.nlm.nih.gov/pubmed/10098765
http://dx.doi.org/10.1038/sj.bjc.6690198