Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53

Differentiated thyroid carcinomas (in contrast to the rarer anaplastic form) are unusual among human cancers in displaying a remarkably low frequency of p53 mutation and appear to retain wild-type (wt) p53 function as assessed by the response of derived cell lines to DNA damage. Using one such cell...

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Detalles Bibliográficos
Autores principales: Wyllie, F S, Haughton, M F, Rowson, J M, Wynford-Thomas, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362227/
https://www.ncbi.nlm.nih.gov/pubmed/10098744
http://dx.doi.org/10.1038/sj.bjc.6690177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362227/
https://www.ncbi.nlm.nih.gov/pubmed/10098744
http://dx.doi.org/10.1038/sj.bjc.6690177

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