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Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53
Differentiated thyroid carcinomas (in contrast to the rarer anaplastic form) are unusual among human cancers in displaying a remarkably low frequency of p53 mutation and appear to retain wild-type (wt) p53 function as assessed by the response of derived cell lines to DNA damage. Using one such cell...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362227/ https://www.ncbi.nlm.nih.gov/pubmed/10098744 http://dx.doi.org/10.1038/sj.bjc.6690177 |