Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells

Loss of DNA mismatch repair has been observed in a variety of human cancers. Recent studies have shown that loss of DNA mismatch repair results in resistance to cisplatin but not oxaliplatin, suggesting that the mismatch repair proteins serve as a detector for cisplatin but not oxaliplatin adducts....

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Detalles Bibliográficos
Autores principales: Nehmé, A, Baskaran, R, Nebel, S, Fink, D, Howell, S B, Wang, J Y J, Christen, R D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362240/
https://www.ncbi.nlm.nih.gov/pubmed/10098743
http://dx.doi.org/10.1038/sj.bjc.6690176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362240/
https://www.ncbi.nlm.nih.gov/pubmed/10098743
http://dx.doi.org/10.1038/sj.bjc.6690176

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