Dual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells

Exposure of some acute myeloid leukaemia (AML) cells to daunorubicin leads to rapid cell death, whereas other AML cells show natural drug resistance. This has been attributed to expression of functional P-glycoprotein resulting in reduced drug accumulation. However, it has also been proposed that P-...

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Detalles Bibliográficos
Autores principales: Côme, M-G, Skladanowski, A, Larsen, A K, Laurent, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362243/
https://www.ncbi.nlm.nih.gov/pubmed/10098741
http://dx.doi.org/10.1038/sj.bjc.6690174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362243/
https://www.ncbi.nlm.nih.gov/pubmed/10098741
http://dx.doi.org/10.1038/sj.bjc.6690174

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