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Dual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells
Exposure of some acute myeloid leukaemia (AML) cells to daunorubicin leads to rapid cell death, whereas other AML cells show natural drug resistance. This has been attributed to expression of functional P-glycoprotein resulting in reduced drug accumulation. However, it has also been proposed that P-...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362243/ https://www.ncbi.nlm.nih.gov/pubmed/10098741 http://dx.doi.org/10.1038/sj.bjc.6690174 |