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Inhibition of transforming growth factor α (TGF-α)-mediated growth effects in ovarian cancer cell lines by a tyrosine kinase inhibitor ZM 252868

The modulating effects of the epidermal growth factor (EGF) receptor-specific tyrosine kinase inhibitor ZM 252868 on cell growth and signalling have been evaluated in four ovarian carcinoma cell lines PE01, PE04, SKOV-3 and PE01(CDDP). Transforming growth factor α (TGF-α)-stimulated growth was compl...

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Detalles Bibliográficos
Autores principales: Simpson, B J B, Bartlett, J M S, Macleod, K G, Rabiasz, G, Miller, E P, Rae, A L, Gordge, P, Leake, R E, Miller, W R, Smyth, J, Langdon, S P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362251/
https://www.ncbi.nlm.nih.gov/pubmed/10098742
http://dx.doi.org/10.1038/sj.bjc.6690175