Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer

To study the involvement of DNA mismatch-repair genes in sporadic breast cancer, matched normal and tumoral DNA samples of 22 patients were analysed for genetic instability and loss of heterozygosity (LOH) with 42 microsatellites at or linked to hMLH1 (3p21), hMSH2 (2p16), hMSH3 (5q11–q13), hMSH6 (2...

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Detalles Bibliográficos
Autores principales: Benachenhou, N, Guiral, S, Gorska-Flipot, I, Labuda, D, Sinnett, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362257/
https://www.ncbi.nlm.nih.gov/pubmed/10098729
http://dx.doi.org/10.1038/sj.bjc.6690162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362257/
https://www.ncbi.nlm.nih.gov/pubmed/10098729
http://dx.doi.org/10.1038/sj.bjc.6690162

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