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Inactivation of the transforming growth factor β type II receptor in human small cell lung cancer cell lines

Transforming growth factor β (TGF-β) exerts a growth inhibitory effect on many cell types through binding to two types of receptors, the type I and II receptors. Resistance to TGF-β due to lack of type II receptor (RII) has been described in some cancer types including small cell lung cancer (SCLC)....

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Detalles Bibliográficos
Autores principales: Hougaard, S, Nørgaard, P, Abrahamsen, N, Moses, H L, Spang-Thomsen, M, Skovgaard Poulsen, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362261/
https://www.ncbi.nlm.nih.gov/pubmed/10098728
http://dx.doi.org/10.1038/sj.bjc.6690161