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Ifosfamide/etoposide alternating with high-dose methotrexate: evaluation of a chemotherapy regimen for poor-risk osteosarcoma

Fifteen patients with relapsed osteosarcoma were treated with an intensive combination chemotherapy schedule. Ifosfamide 2.5 g m(−2) daily and etoposide 150 mg m(−2) daily coincidentally for 3 days and high-dose methotrexate 8 g m(−2) (with folinic acid rescue) on days 10–14 in a planned 21-day cycl...

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Detalles Bibliográficos
Autores principales: Michelagnoli, M P, Lewis, I J, Gattamaneni, H R, Bailey, C C, Lashford, L S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362262/
https://www.ncbi.nlm.nih.gov/pubmed/10098754
http://dx.doi.org/10.1038/sj.bjc.6690187