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Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells
p53 mutations are among the most common genetic alterations in human cancer and are frequently described in intrinsic or acquired radio- and chemotherapy resistance. Radiation-induced cell kill is not only mediated by DNA damage but also by the activation of signal transduction cascades generated at...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362278/ https://www.ncbi.nlm.nih.gov/pubmed/10360645 http://dx.doi.org/10.1038/sj.bjc.6690411 |