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Loss of functional pRB is not a ubiquitous feature of B-cell malignancies
Human cancers frequently sustain genetic mutations that alter the function of their G1 cell cycle control check point. These include changes to the retinoblastoma gene and to the genes that regulate its phosphorylation, such as the cyclin-dependent kinase inhibitor p16(INK4a). Altered expression of...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362291/ https://www.ncbi.nlm.nih.gov/pubmed/10360642 http://dx.doi.org/10.1038/sj.bjc.6690408 |